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関節リウマチ(RA)治療におけるトゥリソキバート(MK-7240)の臨床試験(MK-7240-014)

基本情報

NCT ID
NCT07176390
ステータス
募集中
試験のフェーズ
第2相
試験タイプ
介入
目標被験者数
182
治験依頼者名
Merck Sharp & Dohme LLC

概要

Researchers are looking for new ways to treat rheumatoid arthritis (RA). Methotrexate (MTX) is a standard (usual) treatment for RA. However, MTX and other current treatments may not work well to treat RA symptoms for many people. This study will help find out if a study medicine called tulisokibart can treat symptoms of active RA in people who are taking MTX. In this study, researchers will look at different doses of tulisokibart. Researchers want to learn if at least one of the study doses of tulisokibart works better than a placebo to lessen RA symptoms. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of the study medicine.

対象疾患

関節炎、リウマチ

介入

Tulisokibart(DRUG)
Placebo(DRUG)
Methotrexate(DRUG)

依頼者(Sponsor)

MSD株式会社(INDUSTRY)

実施施設 (8)

佐世保中央病院

Sasebo, Nagasaki, Japan(RECRUITING)

長岡赤十字病院

Nagaoka, Niigata, Japan(RECRUITING)

吉田内科循環器科医院

Hanishina-gun, Nagano, Japan(RECRUITING)

広瀬内科麻酔科医院

Tokorozawa, Saitama, Japan(RECRUITING)

国立大学法人山梨大学医学部附属病院

Chūō, Yamanashi, Japan(RECRUITING)

Hirose Clinic ( Site 2601)

Tokorozawa, Saitama, Japan(RECRUITING)

Kai Clinic ( Site 2600)

Miyazaki, Japan(RECRUITING)

医療法人けいあい かいクリニック

Miyazaki, Japan(RECRUITING)