早期アルツハイマー病患者を対象としたMK-2214の臨床試験(MK-2214-004)
基本情報
- NCT ID
- NCT07033494
- ステータス
- 募集中
- 試験のフェーズ
- 第2相
- 試験タイプ
- 介入
- 目標被験者数
- 340
- 治験依頼者名
- Merck Sharp & Dohme LLC
概要
Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). AD is a type of dementia that can cause loss of memory, communication (such as speech), and decision-making skills. It can limit a person's ability to do daily tasks. MK-2214 is a study treatment designed to slow down AD. The goals of the study are to learn: * If MK-2214 slows the spread of tau in the brain compared to placebo. Tau is a protein that accumulates in AD \& damages brain cells. A placebo looks like the study treatment but has no study treatment in it. Using a placebo helps researchers better understand the effects of a study treatment. * About the safety of MK-2214 and if people tolerate it
対象疾患
介入
依頼者(Sponsor)
実施施設 (13)
独立行政法人国立病院機構 肥前精神医療センター
Kanzaki-gun, Saga-ken, Japan(RECRUITING)
国立研究開発法人国立長寿医療研究センター
Ōbu, Aichi-ken, Japan(RECRUITING)
九州大学病院
Fukuoka, Japan(RECRUITING)
国立大学法人 三重大学医学部附属病院
Tsu, Mie-ken, Japan(RECRUITING)
東京医科大学病院
Shinjuku, Tokyo, Japan(RECRUITING)
社会福祉法人恩賜財団済生会 千葉県済生会習志野病院
Narashino, Chiba, Japan(RECRUITING)
Tokyo Medical University Hospital ( Site 9003)
Shinjuku, Tokyo, Japan(RECRUITING)
岡山市立市民病院
Okayama, Japan(RECRUITING)
医療法人 社団公仁会 城クリニック
Kawasaki, Kanagawa, Japan(RECRUITING)
片山眼科医院
Kurashiki, Okayama-ken, Japan(RECRUITING)
医療法人社団里滋会 片山内科クリニック
Kurashiki, Okayama-ken, Japan(RECRUITING)
稲毛神経内科・メモリークリニック
Chiba, Japan(RECRUITING)
Mie University Hospital ( Site 9011)
Tsu, Mie-ken, Japan(RECRUITING)