経口抗凝固療法が不適切と判断された心房細動の高リスク患者におけるアベラシマブの有効性と安全性を評価する試験（LILAC-TIMI 76）

基本情報

NCT ID: NCT05712200
ステータス: 募集中
試験のフェーズ: 第3相
試験タイプ: 介入
目標被験者数: 1,900
治験依頼者名: Anthos Therapeutics, Inc.

概要

A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been deemed by their responsible physicians or by their own decision to be unsuitable for oral anticoagulation therapy.

対象疾患

心房細動（AF）

介入

Abelacimab(BIOLOGICAL)

Placebo(DRUG)

依頼者（Sponsor）

ノバルティスファーマ株式会社(INDUSTRY)

Anthos Therapeutics(INDUSTRY)

実施施設 (33)

Anthos Investigative Site 1924

Hamamatsu, Japan(RECRUITING)

Anthos Investigative Site 1921

Kōtoku, Japan(RECRUITING)

Anthos Investigative Site 1919

Yokohama, Japan(RECRUITING)

Anthos Investigative Site 1904

Sendai, Japan(RECRUITING)

Anthos Investigative Site 1906

Himeji-Shi, Japan(WITHDRAWN)

Anthos Investigative Site 1902

Chūōku, Japan(RECRUITING)

Anthos Investigative Site 1930

Osaka, Japan(RECRUITING)

Anthos Investigative Site 1909

Tochigi, Japan(RECRUITING)

Anthos Investigative Site 1907

Nagano, Japan(WITHDRAWN)

独立行政法人国立病院機構関門医療センター

Shimonoseki-shi, Japan(WITHDRAWN)

岡山赤十字病院

Okayama, Japan(RECRUITING)

東海大学医学部付属病院

Isehara-Shi, Japan(RECRUITING)

Anthos Investigative Site 1928

Toyama, Japan(RECRUITING)

Anthos Investigative Site 1911

Imabari, Japan(RECRUITING)

Anthos Investigative Site 1910

Hamada-shi, Japan(RECRUITING)

Anthos Investigative Site 1922

Sapporo, Japan(RECRUITING)

独立行政法人国立病院機構愛媛医療センター

Tōon, Japan(RECRUITING)

社会福祉法人恩賜財団済生会支部　福岡県済生会二日市病院

Chikushino-shi, Japan(RECRUITING)

松江市立病院

Matsue, Japan(RECRUITING)

市立宇和島病院

Uwajima-Shi, Japan(RECRUITING)

公益財団法人東京都医療保健協会　練馬総合病院

Tokyo, Japan(RECRUITING)

Anthos Investigative Site 1926

Ōmihachiman, Japan(RECRUITING)

Anthos Investigative Site 1901

Urayasu, Japan(RECRUITING)

徳島大学病院

Tokushima, Japan(RECRUITING)

国家公務員共済組合連合会　呉共済病院

Kure-shi, Japan(RECRUITING)

独立行政法人国立病院機構横浜医療センター

Yokohama, Japan(RECRUITING)

Anthos Investigative Site 1923

Akashi, Japan(RECRUITING)

Anthos Investigative Site 1903

Matsumoto-Shi, Japan(RECRUITING)

大阪公立大学医学部附属病院

Osaka, Japan(RECRUITING)

Anthos Investigative Site 1918

Yokohama, Japan(RECRUITING)

Anthos Investigative Site 1914

Tachikawa-shi, Japan(RECRUITING)

Anthos Investigative Site 1920

Funabashi-Shi, Japan(WITHDRAWN)

地方独立行政法人　那覇市立病院

Naha, Japan(RECRUITING)