被包化壊死に対する即時壊死切除術と段階的アプローチの比較

基本情報

NCT ID: NCT05451901
ステータス: 募集中
試験のフェーズ: 該当なし
試験タイプ: 介入
目標被験者数: 70
治験依頼者名: Tokyo University

概要

Walled-off necrosis (WON) is a pancreatic fluid collection, which contains necrotic tissue after four weeks of the onset of acute pancreatitis. Interventions are required to manage patients with infected WON, for which endoscopic ultrasonography (EUS)-guided drainage has become a first-line treatment modality. For patients who are refractory to EUS-guided drainage, the step-up treatment including endoscopic necrosectomy (EN) and/or additional drainage is considered to subside the infection. Recent evidence suggests that EN immediately after EUS-guided drainage may shorten treatment duration without increasing adverse events. In this randomized trial, the investigators will compare treatment duration between EN immediately after EUS-guided drainage versus the step-up approach in patients with symptomatic WON.

対象疾患

Pancreatic Fluid CollectionWalled-off NecrosisPancreatitis, Acute NecrotizingPancreatic Pseudocyst

介入

Immediate necrosectomy(PROCEDURE)

Step-up approach(PROCEDURE)

依頼者（Sponsor）

Tokyo University(OTHER)

実施施設 (14)

社団医療法人緑風会　高宮消化器科内科医院

Aichi, Japan(RECRUITING)

岐阜県総合医療センター

Gifu, Japan(RECRUITING)

大阪医科薬科大学病院

Osaka, Japan(NOT_YET_RECRUITING)

医療法人鉄蕉会亀田総合病院附属幕張クリニック

Kamogawa, Japan(RECRUITING)

近畿大学病院

Ōsaka-sayama, Japan(NOT_YET_RECRUITING)

医療法人ＩＮＳＹＳＴＥＭ　にしおか内科クリニックＲＡ

Kagoshima, Japan(RECRUITING)

岐阜市民病院

Gifu, Japan(RECRUITING)

さいたま胃腸クリニック

Kawagoe, Japan(NOT_YET_RECRUITING)

三上心療内科・内科医院

Gifu, Japan(NOT_YET_RECRUITING)

医療法人信愛会内科呼吸器科消化器科リハビリテーション科放射線科宇治医院

Bunkyō-Ku, Tokyo, Japan(RECRUITING)

東京大学医学部附属病院

Bunkyō-Ku, Tokyo, Japan(NOT_YET_RECRUITING)

北海道大学病院

Sapporo, Japan(RECRUITING)

千葉大学医学部附属病院

Chiba, Japan(RECRUITING)

株式会社小松製作所本社健康増進センタ金沢健康管理室コマツクリニック

Kanazawa, Japan(NOT_YET_RECRUITING)