代償性進行慢性肝疾患における代償不全リスクを層別化するためのCHESS-SAVEスコア（CHESS2102）

基本情報

NCT ID: NCT04975477
ステータス: 不明
試験のフェーズ: -
試験タイプ: 観察
目標被験者数: 1,000
治験依頼者名: Hepatopancreatobiliary Surgery Institute of Gansu Province

概要

Compensated advanced chronic liver disease (cACLD) was associated with a high rate of variceal bleeding, ascites, and hepatic encephalopathy due to portal hypertension. In these patients, esophagogastroduodenoscopy and hepatic venous pressure gradient were recommended methods to evaluate portal hypertension. However, non-invasive predictors of outcomes to stratify care remains needed. Although the updated EASL guideline has recommended that patients with liver stiffness \>20kPa or platelets \<150\*10\^9/L had the high risk of decompensation, the criteria remains to be validated. This international multicenter study aims to develop a novel CHESS-SAVE score to further predict the risk of liver decompensation in cACLD patients.