健康成人におけるS-648414の単回および複数回投与時の安全性、忍容性、薬物動態、薬物相互作用および食物相互作用の評価

基本情報

NCT ID

NCT04147715

ステータス

完了

試験のフェーズ

第1相

試験タイプ

介入

目標被験者数

98

治験依頼者名

Shionogi Inc.

概要

The primary objective of Part 1 of the study is to evaluate the safety and tolerability of S-648414 after administration of a single oral dose of S-648414 in healthy adult study participants. The primary objective of Part 2 is to evaluate the safety and tolerability of S-648414 after administration of multiple oral doses of S-648414 in healthy adult study participants. The primary objectives of Part 3 are evaluate the safety and tolerability of S-648414 after administration of multiple oral doses of S-648414 in healthy adult study participants, and to evaluate the effect of S-648414 on the pharmacokinetics (PK) of dolutegravir and the effect of dolutegravir on the PK of S-648414 in healthy adult study participants.

対象疾患

介入

依頼者（Sponsor）

実施施設 (1)