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うつ伏せ姿勢と自発呼吸
基本情報
- NCT ID
- NCT03768154
- ステータス
- 不明
- 試験のフェーズ
- 第1相
- 試験タイプ
- 介入
- 目標被験者数
- 12
- 治験依頼者名
- Osaka University
概要
Spontaneous breathing during mechanical ventilation has been recommended in patients with ARDS and is currently used. in part because oxygenation is better and there is a lower risk of diaphragm dysfunction due to disuse. The other approach to minimizing lung injury from spontaneous effort is the use of neuromuscular blockade; an early and short term (48 hours) of neuromuscular blockade in patients with severe ARDS has been shown to decrease inflammation and to improve survival. The investigators propose a pilot study to test the feasibility and the physiological effects of allowing spontaneous breathing in the prone position in patients with ARDS.
対象疾患
Critical IllnessARDS
介入
Supine + spontaneous effort(PROCEDURE)
Supine + paralysis(PROCEDURE)
Prone + paralysis(PROCEDURE)
Prone + spontaneous breathing(PROCEDURE)
依頼者(Sponsor)
Osaka University(OTHER)
Hospital Rebagliati(UNKNOWN)
実施施設 (1)
大阪大学医学部附属病院
Suita, Osaka, Japan