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中等度から重度のアトピー性皮膚炎を有する成人患者に投与されたREGN3500の有効性、安全性、および薬物動態プロファイル

基本情報

NCT ID
NCT03738423
ステータス
中止
試験のフェーズ
第2相
試験タイプ
介入
目標被験者数
129
治験依頼者名
Regeneron Pharmaceuticals

概要

The primary objective of the study is to assess the efficacy of REGN3500 monotherapy in Atopic dermatitis (AD), as well as understand the dose-response relationship, compared with placebo treatment, in adult patients with moderate-to-severe AD. Secondary objectives are to: * Assess the safety and tolerability of subcutaneous (SC) doses of REGN3500 monotherapy in adult patients with moderate-to-severe AD * Assess the Pharmacokinetics (PK) of REGN3500 in adult patients with moderate-to-severe AD * Assess the immunogenicity of REGN3500 in adult patients with moderate-to-severe AD

対象疾患

Atopic Dermatitis

介入

REGN3500(DRUG)
REGN3500-Matching Placebo(DRUG)

依頼者(Sponsor)