多関節型若年性特発性関節炎の小児患者におけるウパダシチニブの薬物動態、安全性および忍容性を評価する試験

基本情報

NCT ID

NCT03725007

ステータス

実施中（募集終了）

試験のフェーズ

第1相

試験タイプ

介入

目標被験者数

124

治験依頼者名

AbbVie

概要

This is a study to evaluate pharmacokinetics, safety and tolerability of upadacitinib in pediatric participants with polyarticular course juvenile idiopathic arthritis. This study consists of three parts: Part 1 is multiple-cohort study that consists of two sequential multiple dose groups. Participants benefiting from the study drug with no ongoing adverse events of special interest or serious adverse events will have option to enroll in Part 2. Part 2 is open-label, long term extension study to evaluate safety and tolerability. Part 3 is an additional safety cohort to evaluate long-term safety and tolerability.

対象疾患

介入

依頼者（Sponsor）

実施施設 (7)