アジアダウン症候群急性リンパ性白血病2016

基本情報

NCT ID: NCT03286634
ステータス: 募集中
試験のフェーズ: 第2相
試験タイプ: 介入
目標被験者数: 60
治験依頼者名: National Hospital Organization Nagoya Medical Center

概要

To evaluate the outcome of a prednisolone and low dose methotrexate based protocol in Down syndrome children with ALL (DS-ALL) in an Asia-wide study. The treatment protocol was modified based upon backbone of Taiwan Pediatric Oncology Group (TPOG)-ALL protocol in which risk classification will be guided by level of flow minimal residual disease (MRD) instead.

対象疾患

Down SyndromeAcute Lymphoblastic LeukemiaChildhood Cancer

介入

Daunorubicin(DRUG)

Prednisolone(DRUG)

Vincristine(DRUG)

Epirubicin(DRUG)

E-coli L-asparaginase(DRUG)

6-Mercaptopurine(DRUG)

Methotrexate(DRUG)

Hydrocortisone(DRUG)

Cytarabine(DRUG)

Cyclophosphamide(DRUG)

依頼者（Sponsor）

National Hospital Organization Nagoya Medical Center(OTHER)

実施施設 (1)

鹿児島大学病院

Kagoshima, Japan(RECRUITING)