がんおよび心血管疾患の病原メカニズム

基本情報

NCT ID

NCT03051191

ステータス

完了

試験のフェーズ

-

試験タイプ

観察

目標被験者数

66

治験依頼者名

Sakakibara Heart Institute

概要

Subjects with cardiovascular diseases (CVD) have higher incidence of cancers compared to general population. The investigators hypothesized that shared molecular mechanism play a pivotal role in the pathogenesis of CVD including heart failure (HF) and cancers. To address this hypothesis, the investigators are going to explore the expression pattern of micro RNA (miRNA) and cell free DNA (cfDNA) derived from host, gut microbiota and gut microbiota composition extensively in patients with or without CVD, non-ischemic HF (NIHF), and cancers. The participants will be recruited from the outpatient clinic in Sakakibara Heart Institute or Japanese Foundation for Cancer Research. By comparing the expression pattern of miRNA, cfDNA, or gut microbiota composition, the investigators are seeking to find the pathogenic mechanisms shared by those diseases.

対象疾患

介入

依頼者（Sponsor）

実施施設 (2)