TRK-700とジゴキシンおよびミダゾラムとの薬物相互作用に関する研究

基本情報

NCT ID: NCT03043248
ステータス: 完了
試験のフェーズ: 第1相
試験タイプ: 介入
目標被験者数: 48
治験依頼者名: Toray Industries, Inc

概要

This study comprises 2 cohorts, and in each cohort, the study will be conducted as an open-label add-on study. The purpose of the study is to investigate the pharmacokinetics of each substrate in concomitant administration of a single dose of the P-glycoprotein substrate digoxin (Cohort A) or the CYP3A4 substrate midazolam (Cohort B) during repeated administration of TRK-700 in healthy adult males.

対象疾患

Healthy

介入

TRK-700(DRUG)

Digoxin(DRUG)

Midazolam(DRUG)

依頼者（Sponsor）

Toray Industries(INDUSTRY)