多施設国際横断的肺胞蛋白症評価試験

基本情報

NCT ID

NCT03007134

ステータス

完了

試験のフェーズ

-

試験タイプ

観察

目標被験者数

73

治験依頼者名

Children's Hospital Medical Center, Cincinnati

概要

The purpose of this study is to (1) compare a technically improved assay with an existing assay used to measure serum anti-GM-CSF antibodies in stored serum samples previously obtained from patients diagnosed with either primary, secondary, congenital or idiopathic pulmonary alveolar proteinosis (PAP), other chronic diseases or disease-free, healthy individuals; (2) determine the prevalence and levels of anti-GM-CSF autoantibodies and (3) define the breadth of the autoimmune antibody responses in primary PAP patients from the United States, Japan, Australia, and Europe using previously collected serum samples; and (4) using a chart review approach, compare the clinical, radiologic and laboratory features of primary PAP patients to determine if differences exist among patients in these globally geographically distributed regions.

対象疾患

介入

依頼者（Sponsor）

実施施設 (2)