ピロリ菌除菌におけるボノプラザンベースの二剤併用療法と三剤併用療法の比較

基本情報

NCT ID: NCT02827942
ステータス: 完了
試験のフェーズ: 第3相
試験タイプ: 介入
目標被験者数: 112
治験依頼者名: Hamamatsu University

概要

Patients infected with H. pylori were randomly assigned to the dual therapy with vonoprazan 20 mg bid and amoxicillin 500 mg tid for 1 week or the triple therapy with vonoprazan 20 mg bid, amoxicillin 750 mg bid and clarithromycin 200 mg or metronidazole 250 mg bid bid for 1 week. Success or failure of eradication was determined by the 13C-urea breath test performed at 1 month after the therapy.

対象疾患

Gastritis Associated With Helicobacter Pylori

介入

vonoprazan 20 mg bid(DRUG)

Amoxicillin 500 mg tid(DRUG)

Amoxicillin 750 mg bid(DRUG)

Clarithromycin 200 mg bid(DRUG)

Metronidazole 250 mg bid(DRUG)

依頼者（Sponsor）

Hamamatsu University(OTHER)

実施施設 (1)

浜松医科大学医学部附属病院

Hamamatsu, Shizuoka, Japan