うっ血性心不全を伴う糖尿病患者におけるDPP-4阻害薬と血清BNP値

基本情報

NCT ID: NCT02312427
ステータス: 完了
試験のフェーズ: 第4相
試験タイプ: 介入
目標被験者数: 10
治験依頼者名: Mitsui Memorial Hospital

概要

We thought to investigate the influence of DPP-4 inhibitor on the serum BNP level of diabetic patients with congestive heart failure. This study consists of two protocols. In the first protocol, diabetic patients with high level of serum BNP (100-2000 pg/ml) receiving outpatient treatment with any type of DPP-4 inhibitor at our institution will be enrolled. After baseline data collection, DPP-4 inhibitor will be suspended for one month and serum BNP will be measured. The DPP-4 inhibitor will be resumed and after another month, serum BNP will be measured again. In the other protocol, diabetic patients who were hospitalized due to heart failure were enrolled. DPP-4 inhibitor will be started (if the patient is not taking a DPP-4 inhibitor) or suspended (if the patient is taking a DPP-4 inhibitor) after stabilization of heart failure, and serum BNP will be measured before and after the drug administration or suspension.

対象疾患

Heart FailureDiabetes Mellitus

介入

Suspending DPP-4 inhibitor, in outpatient service(DRUG)

Starting DPP-4 inhibitor after treatment of heart failure(DRUG)

Suspending DPP-4 inhibitor after treatment of heart failure(DRUG)

依頼者（Sponsor）

Mitsui Memorial Hospital(OTHER)

Mitsukoshi Health And Welfare Foundation(INDUSTRY)

実施施設 (1)

社会福祉法人　三井記念病院

Taito-ku, Tokyo, Japan