2型糖尿病患者における経口ブドウ糖負荷試験中のシタグリピチンの内皮機能への影響

基本情報

NCT ID: NCT02301806
ステータス: 不明
試験のフェーズ: 第4相
試験タイプ: 介入
目標被験者数: 30
治験依頼者名: Dokkyo Medical University

概要

To investigate whether single administration of sitaglitpin can restore acute endothelial dysfunction and ameliorate impaired increase of the number of endothelial progenitor cells (EPCs) after oral glucose loading in patients with T2DM. To compare the effect of sitagliptin and glimepiride on endothelial function evaluated by flow-mediated vasodilatation (FMD) and the number of circulating EPCs in patients with T2DM.

対象疾患

Type 2 Diabetes

介入

dieting(OTHER)

Sitagliptin(DRUG)

Glimepiride(DRUG)

依頼者（Sponsor）

MSD株式会社(INDUSTRY)

Dokkyo Medical University(OTHER)

実施施設 (1)

Dokkyo Medical University

Mibu, Tochigo, Japan(RECRUITING)