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長時間にわたる脳神経外科手術における、全静脈麻酔法からデスフルラン麻酔法への切り替え

基本情報

NCT ID
NCT01985854
ステータス
不明
試験のフェーズ
第4相
試験タイプ
介入
目標被験者数
60
治験依頼者名
Tokyo Women's Medical University

概要

Since neurological testing during neurosurgery, such as somato-sensory evoked potentials, motor-evoked potentials, auditory evoked potentials and visual evoked potentials are well maintained their wave-form reactivity with total intravenous anaesthesia technique better than inhalational anesthetic techniques, the standard anesthesia method for neurosurgery is usually total intravenous anaesthesia technique. Nonetheless, after finishing recording the evoked potential responses during surgery, facilitation of recovery from general anesthesia is getting important, because the real neurological physical examination is much more sensitive than above electrical evoked potentials to evaluate the results of surgical operation. We propose to evaluate the recovery parameters after conversion from total intravenous anaesthesia technique to Desflurane anesthesia during long term neurosurgery procedures. The conversion will be initiated upon completion of the neurophysiological electric evoked potentials assessment. Based on the pharmacological properties of desflurane, we hypothesize that recovery after conversion to Desflurane will be faster compared to recovery after total intravenous anaesthesia alone.

対象疾患

Patients Undergoing Elective Craniotomy

介入

Propofol(DRUG)
Desflurane(DRUG)

依頼者(Sponsor)

実施施設 (1)

東京女子医科大学病院

Tokyo, Tokyo, Japan