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HLA-A*24疾患をコントロールした進行非小細胞肺癌に対するエピトープペプチドの安全性および有効性に関する研究

基本情報

NCT ID
NCT01950156
ステータス
完了
試験のフェーズ
第1/第2相
試験タイプ
介入
目標被験者数
6
治験依頼者名
Shiga University

概要

The investigators previously identified three novel HLA-A\*2402-restricted epitope peptides, which were derived from three cancer-testis antigens, URLC10, CDCA1, and KIF20A, as targets for vaccination against lung cancer. In this clinical study, the investigators examine using a combination of these three peptides the safety, immunogenicity, and antitumor effect of vaccine treatment to prevent relapse of the disease for HLA-A\*2402-positive advanced non-small cell lung cancer patients whose disease are controlled after any standard therapies.

対象疾患

Non-small Cell Lung Cancer

介入

HLA-A*2402restricted URLC10, CDCA1, and KIF20A peptides with adjuvant(BIOLOGICAL)

依頼者(Sponsor)

実施施設 (1)

滋賀医科大学医学部附属病院

Ōtsu, Shiga, Japan