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HLA-A*24疾患をコントロールした進行非小細胞肺癌に対するエピトープペプチドの安全性および有効性に関する研究
基本情報
- NCT ID
- NCT01950156
- ステータス
- 完了
- 試験のフェーズ
- 第1/第2相
- 試験タイプ
- 介入
- 目標被験者数
- 6
- 治験依頼者名
- Shiga University
概要
The investigators previously identified three novel HLA-A\*2402-restricted epitope peptides, which were derived from three cancer-testis antigens, URLC10, CDCA1, and KIF20A, as targets for vaccination against lung cancer. In this clinical study, the investigators examine using a combination of these three peptides the safety, immunogenicity, and antitumor effect of vaccine treatment to prevent relapse of the disease for HLA-A\*2402-positive advanced non-small cell lung cancer patients whose disease are controlled after any standard therapies.
対象疾患
Non-small Cell Lung Cancer
介入
HLA-A*2402restricted URLC10, CDCA1, and KIF20A peptides with adjuvant(BIOLOGICAL)
依頼者(Sponsor)
Shiga University(OTHER)
Tokyo University(OTHER)
実施施設 (1)
滋賀医科大学医学部附属病院
Ōtsu, Shiga, Japan