内皮機能障害とプラークの脆弱性

基本情報

NCT ID

NCT01578616

ステータス

完了

試験のフェーズ

-

試験タイプ

観察

目標被験者数

100

治験依頼者名

Yokohama City University Medical Center

概要

Thinning of fibrous cap in atherosclerotic plaques is associated with plaque vulnerability. The high resolution of optical coherence tomography (OCT) provides an accurate measurement of fibrous cap thickness. Endothelial dysfunction is a key component of vulnerable plaque and digital reactive hyperemia-peripheral arterial tonometry (RH-PAT) is a non-invasive automatic and quantitative method to evaluate endothelial function. The investigators will investigate the association between endothelial function assessed by RH-PAT and plaque vulnerability determined by OCT-derived thin-cap fibroatheroma (TCFA).

対象疾患

依頼者（Sponsor）

実施施設 (1)