シェーグレン症候群における共焦点顕微鏡検査と涙腺

基本情報

NCT ID

NCT00920179

ステータス

不明

試験のフェーズ

-

試験タイプ

観察

目標被験者数

30

治験依頼者名

Keio University

概要

Traditional methodological clinical and instrumental diagnostics of the lacrimal gland for the study of glandular architecture and functions are limited and include analysis of tear constituents, evaluation of apparent diffusion coefficients in magnetic resonance imaging and histopathological evaluation of lacrimal gland biopsy specimens. Confocal microscopy is a new emerging technology which is useful as a supplementary diagnostic tool for in vivo assessment of anterior-segment disorders.The use of in vivo confocal microscopy in a comparative study of the microscopic morphology of the salivary/lacrimal glands have not been reported up to date. In this study, we employ laser scanning confocal microscopy to evaluate the morphological changes of the salivary/lacrimal glands in patients with primary Sjögren's syndrome and compare the results with those of healthy control subjects.

対象疾患

依頼者（Sponsor）

実施施設 (1)