エイコサペンタエン酸による脳血管攣縮治療に関する研究

基本情報

NCT ID: NCT00839449
ステータス: 完了
試験のフェーズ: 第4相
試験タイプ: 介入
目標被験者数: 200
治験依頼者名: Yamaguchi University Hospital

概要

Cerebral vasospasm following subarachnoid hemorrhage (SAH) is the most common cause of morbidity and mortality. Recent studies indicate that Rho-kinase play an important role in the occurrence of such cerebral vasospasm. Eicosapentaenoic acid (EPA) inhibits sphingosylphosphorylcholine (SPC)-induced Rho-kinase activation in vitro. So this study examines whether EPA prevents cerebral vasospasm occurrence after SAH in patients.