朝の高血圧と優れた治療法に関する研究

基本情報

NCT ID

NCT00795847

ステータス

完了

試験のフェーズ

第4相

試験タイプ

介入

目標被験者数

216

治験依頼者名

Kurume University

概要

It is difficult to control morning hypertension in practical clinical situation. Angiotensin receptor blocker (ARB) and thiazide are suggested to be effective to maintain the antihypertensive effects for 24 hours. However, monotherapy sometimes is not enough to control blood pressure level in the next morning and there are little evidence of the combination therapy for morning hypertension. The investigators hypothesized that a losartan 50 mg/hydrochlorothiazide 12.5 mg combination drug, Preminent, is effective and safe for controling morning hypertension, compared with high-dose of losartan 100 mg, in Japanese. Patients with morning hypertension were randomized to preminent treatment group or high-dose losartan treatment group. The efficacy and safety were compared after 3-month treatment.

対象疾患

介入

依頼者（Sponsor）

実施施設 (1)