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慢性喫煙が循環内皮細胞および血小板由来微粒子に及ぼす影響

基本情報

NCT ID
NCT00795249
ステータス
完了
試験のフェーズ
早期第1相
試験タイプ
介入
目標被験者数
100
治験依頼者名
Kurume University

概要

The investigators hypothesized that circulating EMP is a useful surrogate marker of early stage of endothelial damage. To determine the effects of chronic smoking on circulating EMP, from healthy volunteers who have habit of chronic smoking, peripheral blood is drawn at the time of flow-mediated dilatation (FMD) examination. Spot urine is also collected. Circulating EMPs are counted using flow-cytometry. After 2-week smoking cessation, the measurements were repeated.

対象疾患

Atherosclerosis

介入

smoking cessation(BEHAVIORAL)

依頼者(Sponsor)

実施施設 (1)

久留米大学病院

Kurume, Fukuoka, Japan