手術により完全に切除されたステージIII結腸癌患者の治療におけるテガフール・ウラシルとロイコボリンまたはS-1の併用療法

基本情報

NCT ID: NCT00660894
ステータス: 完了
試験のフェーズ: 第3相
試験タイプ: 介入
目標被験者数: 1,535
治験依頼者名: Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

概要

RATIONALE: Drugs used in chemotherapy, such as tegafur-uracil, leucovorin, and S-1, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving tegafur-uracil together with leucovorin is more effective than giving S-1 in treating patients with stage III colon cancer. PURPOSE: This randomized phase III trial is studying giving tegafur-uracil together with leucovorin to see how well it works compared with giving S-1 in treating patients with stage III colon cancer that has been completely removed by surgery.

対象疾患

Colorectal Cancer

介入

folinate calcium(DRUG)

tegafur-uracil(DRUG)

tegafur-gimeracil-oteracil potassium(DRUG)

依頼者（Sponsor）

Translational Research Center For Medical Innovation, Kobe, Hyogo, Japan(OTHER)

実施施設 (1)

東京科学大学病院

Tokyo, Tokyo, Japan