未治療のステージIIIまたはステージIV非小細胞肺癌患者に対するパクリタキセルとカルボプラチン（ニトログリセリン併用または非併用）による治療

基本情報

NCT ID: NCT00616031
ステータス: 不明
試験のフェーズ: 第2相
試験タイプ: 介入
目標被験者数: 150
治験依頼者名: National Cancer Institute (NCI)

概要

RATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Nitroglycerin may help carboplatin and paclitaxel work better by making tumor cells more sensitive to the drugs. PURPOSE: This phase II randomized trial is studying how well giving nitroglycerin together with paclitaxel and carboplatin works and compares it to giving paclitaxel and carboplatin alone in treating patients with previously untreated stage III or stage IV non-small cell lung cancer.

対象疾患

Lung Cancer

介入

carboplatin(DRUG)

nitroglycerin(DRUG)

paclitaxel(DRUG)

依頼者（Sponsor）

Translational Research Center For Medical Innovation, Kobe, Hyogo, Japan(OTHER)

Kyoto University(OTHER)

実施施設 (1)

京都大学医学部附属病院

Kyoto, Kyoto, Japan(RECRUITING)