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メニエール病におけるバソプレシンとV2受容体

基本情報

NCT ID
NCT00599560
ステータス
完了
試験のフェーズ
該当なし
試験タイプ
介入
目標被験者数
135
治験依頼者名
Osaka University

概要

Summary: Some of sicknesses are well known to be provoked by inadequate adaptation to physical and/or psychogenic stress in their daily life. Meniere's disease is also a common inner ear disease accompanied with vertigo, hearing loss and tinnitus especially in civilized people under stressed life style. Its oto-pathology was firstly revealed in 1938 to be inner ear endolymphatic hydrops through the temporal bone study. To elucidate the neuroscientific relationship between "stress" and "inner ear", we examined plasma vasopressin (the anti-diuretic "stress" hormone) and its receptor, V2R in the endolymphatic sac (the "inner ear" endo-organ for endolymph absorption) in Meniere's patients.

対象疾患

Meniere Disease

介入

vasopressin, V2 receptor and cyclic AMP(GENETIC)

依頼者(Sponsor)

実施施設 (1)

大阪大学医学部附属病院

Suita, Osaka, Japan