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メニエール病におけるバソプレシンとV2受容体
基本情報
- NCT ID
- NCT00599560
- ステータス
- 完了
- 試験のフェーズ
- 該当なし
- 試験タイプ
- 介入
- 目標被験者数
- 135
- 治験依頼者名
- Osaka University
概要
Summary: Some of sicknesses are well known to be provoked by inadequate adaptation to physical and/or psychogenic stress in their daily life. Meniere's disease is also a common inner ear disease accompanied with vertigo, hearing loss and tinnitus especially in civilized people under stressed life style. Its oto-pathology was firstly revealed in 1938 to be inner ear endolymphatic hydrops through the temporal bone study. To elucidate the neuroscientific relationship between "stress" and "inner ear", we examined plasma vasopressin (the anti-diuretic "stress" hormone) and its receptor, V2R in the endolymphatic sac (the "inner ear" endo-organ for endolymph absorption) in Meniere's patients.
対象疾患
Meniere Disease
介入
vasopressin, V2 receptor and cyclic AMP(GENETIC)
依頼者(Sponsor)
Osaka University(OTHER)
Osaka City University(OTHER)
実施施設 (1)
大阪大学医学部附属病院
Suita, Osaka, Japan