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新たに診断された多形性膠芽腫の高齢患者に対する放射線療法(テモゾロミド併用または非併用)
基本情報
- NCT ID
- NCT00482677
- ステータス
- 完了
- 試験のフェーズ
- 第3相
- 試験タイプ
- 介入
- 目標被験者数
- 562
- 治験依頼者名
- Canadian Cancer Trials Group
概要
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with temozolomide may kill more tumor cells. It is not yet known whether radiation therapy and temozolomide are more effective than radiation therapy alone in treating glioblastoma multiforme. PURPOSE: This randomized phase III trial is studying radiation therapy and temozolomide to see how well they work compared with radiation therapy alone in treating patients with newly diagnosed glioblastoma multiforme.
対象疾患
Brain and Central Nervous System Tumors
介入
temozolomide(DRUG)
DNA methylation analysis(GENETIC)
quality-of-life assessment(PROCEDURE)
Radiation(RADIATION)
依頼者(Sponsor)
実施施設 (1)
広島大学病院
Hiroshima, Japan