局所進行子宮頸がんまたは高リスク子宮内膜がん患者におけるリンパ節転移の発見における、化学療法および放射線療法前のフルデオキシグルコース（FDG）F 18 PETスキャン、CTスキャン、およびフェルモクストラン-10 MRIスキャン

基本情報

NCT ID: NCT00416455
ステータス: 完了
試験のフェーズ: 第1/第2相
試験タイプ: 介入
目標被験者数: 384
治験依頼者名: National Cancer Institute (NCI)

概要

This phase I/II trial is studying how well fludeoxyglucose F 18 PET scan, CT scan, and ferumoxtran-10 MRI scan finds lymph node metastasis before undergoing chemotherapy and radiation therapy in patients with locally advanced cervical cancer or high-risk endometrial cancer. Diagnostic procedures, such as a fludeoxyglucose F 18 positron emission tomography (PET) scan, computed tomography (CT) scan, and ferumoxtran-10 magnetic resonance imaging (MRI) scan, may help find lymph node metastasis in patients with cervical cancer or endometrial cancer.

対象疾患

Cervical AdenocarcinomaCervical Adenosquamous Cell CarcinomaCervical Small Cell CarcinomaCervical Squamous Cell CarcinomaEndometrial Clear Cell CarcinomaEndometrial Papillary Serous CarcinomaStage I Endometrial CarcinomaStage IB Cervical CancerStage II Endometrial CarcinomaStage IIA Cervical CancerStage IIB Cervical CancerStage III Cervical CancerStage III Endometrial CarcinomaStage IVA Cervical Cancer

介入

fludeoxyglucose F 18(RADIATION)

positron emission tomography(PROCEDURE)

computed tomography(PROCEDURE)

ferumoxtran-10(DRUG)

magnetic resonance imaging(PROCEDURE)

diagnostic lymphadenectomy(PROCEDURE)

lymph node biopsy(PROCEDURE)

依頼者（Sponsor）

Nrg Oncology(OTHER)

National Cancer Institute (Nci)(NIH)

実施施設 (3)

鹿児島市立病院

Kagoshima City, Kagoshima, Japan

北海道大学病院

Sapporo, Hokkaido, Japan

埼玉医科大学国際医療センター

Saitama, Japan