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日本における再発性脳卒中に対するスタチン治療に関するhsCRP研究(J-STARS hsCRP)

基本情報

NCT ID
NCT00361699
ステータス
完了
試験のフェーズ
第3相
試験タイプ
介入
目標被験者数
1,095
治験依頼者名
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

概要

Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase can play a role in preventing recurrent vascular events from ischemic heart disease patients, whose mechanism consists in not only the reduction of serum lipid level but also anti-inflammatory effects. Serum high sensitive CRP is known to be a predictor of cardiovascular events independent of other conventional risk factors. The present substudy examine whether such pleiotrophic effect of HMG-CoA reductase inhibitor (statin) which decreases high sensitive CRP would be observed in the post-ischemic stroke patients who have already been registered in the J-STARS, and the relationship the values of high sensitive CRP and recurrence of stroke.

対象疾患

Ischemic Stroke

介入

Statin(DRUG)

実施施設 (2)

広島大学病院

Hiroashima, Hiroshima, Japan

大阪大学医学部附属病院

Suita-shi, Osaka, Japan