日本における再発性脳卒中に対するスタチン治療に関するhsCRP研究(J-STARS hsCRP)
基本情報
- NCT ID
- NCT00361699
- ステータス
- 完了
- 試験のフェーズ
- 第3相
- 試験タイプ
- 介入
- 目標被験者数
- 1,095
- 治験依頼者名
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
概要
Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase can play a role in preventing recurrent vascular events from ischemic heart disease patients, whose mechanism consists in not only the reduction of serum lipid level but also anti-inflammatory effects. Serum high sensitive CRP is known to be a predictor of cardiovascular events independent of other conventional risk factors. The present substudy examine whether such pleiotrophic effect of HMG-CoA reductase inhibitor (statin) which decreases high sensitive CRP would be observed in the post-ischemic stroke patients who have already been registered in the J-STARS, and the relationship the values of high sensitive CRP and recurrence of stroke.
対象疾患
介入
依頼者(Sponsor)
実施施設 (2)
広島大学病院
Hiroashima, Hiroshima, Japan
大阪大学医学部附属病院
Suita-shi, Osaka, Japan