家庭血圧測定に基づく高血圧管理

基本情報

NCT ID

NCT00198562

ステータス

不明

試験のフェーズ

第4相

試験タイプ

介入

目標被験者数

2,600

治験依頼者名

Ministry of Health, Labour and Welfare, Japan

概要

The aim of this trial is to study the effects of antihypertensive therapy based on home systolic blood pressure (BP) with different target levels using two classes of drugs. The HOSP study is a multicenter, prospective, randomized, open, blinded endpoint study. The study subjects are 40-79 years old hypertensive patients. After a 4 weeks of baseline period, subjects are randomly assigned to (1) modest control group (morning home BP \<140 mmHg) or (2) strict control group (morning home BP \<130 mmHg), and to (a) amlodipine group or (b) losartan group. Additional antihypertensive drugs can be used if home BP is not controlled. Home BP is measured in the early morning and late evening. The participants will be followed up for 5 years.

対象疾患

介入

依頼者（Sponsor）

実施施設 (1)